BIO-NANO-ROBO Seminar Series

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Every month, LIMMS and CNRS Japon organize the BIO-NANO-ROBO Seminar series that will gather together Japanese and International industrials and academics to attend two lectures given by two outstanding researchers in cutting edge areas of Science.

- Schedule: Check the Seminar Series Schedule

- Contact: Sebastian Volz, Dr. , Dominique FOURMY, Dr.

Contents

NEXT SEMINAR SERIES

BIO-NANO-ROBO Seminar Series Announcement
December 18th 2009 at PM 2:00
C-lounge, Building C, 2nd floor
IIS-University of Tokyo, Komaba 4-6-1, Meguro-ku, Tokyo 153-8505.

Pr. Vincent CROQUETTE
Laboratoire de Physique Statistique, Ecole Normale Superieure, Paris Center, NIMS

Title : Single DNA molecule micromanipulation by magnetic tweezers : a tool to investigate enzymatic reactions.

Abstract :

In the last ten years, micromanipulation techniques have emerged allowing for the investigation of enzymatic reactions at the single molecule level. We use magnetic tweezers to pull and twist a micron size bead attached to one end of a DNA molecule by biotin/streptavidin while the second end is attached to a glass slide by digoxigenin/antibody. Monitoring the position of the bead with nanometer resolution allows us to record the minute changes caused by a single enzyme interacting with the DNA molecule ... Download the Abstract

BIO-NANO-ROBO Seminar Series Announcement
October 29th 2009 at PM 5:00
C-lounge, Building C, 2nd floor
IIS-University of Tokyo, Komaba 4-6-1, Meguro-ku, Tokyo 153-8505.

Pr. Akiyoshi TANIGUCHI
Biomaterials Center, NIMS

Title : Live cell-based sensor devices

Abstract :
InLiving cells maintain life functions by responding quickly and with great sensitivity to changes in the external environment. Consequently, sensors using cells as active elements are thought to be able to perform analyses faster and with more sensitivity than previously possible. We report here a live cells-based sensorchip fabricated in microfluidic channels in which several laminar flows were achieved. In addition, we established a cytotoxic sensor cell line, which was transfected with a green fluorescence protein (GFP) plasmid derived from the heat shock protein 70B’ (HSP70B’) promoter, which is induced by cytotoxic reagents. The fluorescence in the sensor cells increased in a CdCl2 dose-dependent manner in the microfluidic channels. In this system, cytotoxic reagents can be quantitatively detected in a quick, sensitive and high- throughput manner. The combination of sensor cells and microfluidic systems will provide an important basis for the development of micro-total analysis systems (micro-TAS) technology, and can be applied to toxicology, environmental assessment and drug screening.
Image:Pdf_icon.png Live cell-based sensor devices Image:Info_circle.png


BIO-NANO-ROBO Seminar Series Announcement
September 25th, 2009, 17h-18h, Room Dw601 , 6th floor.
Pr. Masami HAGIYA
Department of Computer Science
Graduate School of Information Science and Technology (Univ. Tokyo)
Title : DNA Nanotechnology, Nanorobotics, DNA Computing, Synthetic Biology and Beyond
Abstract :
In this talk, I explain how to make small things out of DNA (DNA nanotechnology), how to incorporate dynamic components into static structures (DNA nanorobotics), and how to process information by DNA (DNA computing). I also briefly introduce synthetic biology while regarding DNA nanorobotics as its warming-up exercise. Finally, I touch on open science (Science2.0) and science automation in connection with synthetic biology. The talk includes our recent work on DNA comparator, a kind of DNA logic gate (DNA computing) and our current work on automatically designing DNA nanomachines (science automation).

BIO-NANO-ROBO Seminar Series Announcement
July 29th, 2009, 17h-18h, Room Dw601 , 6th floor.
Pr. Jean-Claude PORTAL (Institut Universitaire de France) will give a special talk about "Electronic Ratchet effect under Microwave Radiations".
Download the Abstract

BIO-NANO-ROBO Seminar Series Announcement
June 29th, 2009, 17h-18h, Room Dw601 , 6th floor.
Pr. Michio TOMISHIGE
University of Tokyo
Image:Pdf_icon.png Single molecule structural observations of a "walking" molecular motor protein Image:Info_circle.png
Download the Abstract


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UPCOMING and PAST SEMINAR SERIES

BIO-NANO-ROBO Seminar Series Announcement'
December 10th, 2008, 17h-18h, Room An401-402, Building A , 4th floor.
Dr. Masayuki YAMATO
Institute of Advanced Biomedical Engineering and Science, Tokyo Women's Medical University, Japan

Image:Pdf_icon.png Nanotechnology-based Cell Sheet Engineering for Regenerative Medicine Image:Info_circle.png

Abstract :
Here, we present unique tissue engineering without biodegradable polymer scaffolds, named cell sheet engineering. We first developed temperature-responsive culture dishes. A temperature-responsive poly- mer, poly(N-isopropylacrylamide), is covalently grafted on the surfaces. The grafted polymer thickness is controlled around 20 nm to achieve temperature-responsive cell adhesion/detachment control. The surfaces of temperature-responsive culture dishes are relatively hydrophobic at 37 degrees C similarly to commercially available tissue culture dishes, but changes to hydrophilic below 32 degrees C. Various cell types adhere, spread, and proliferate on the surfaces at 37 degrees C. Only by reducing temperature, cells are spontaneously lifted up from the surfaces without the need for trypsin. Confluently cultured cells are recovered as a single contiguous cell sheet with intact cell-cell junctions and deposited extracellular matrix. Harvested viable cell sheets can be transferred to other surfaces of culture dishes in vitro or tissue surfaces in vivo since the extracellular matrix associated with the basal side of cell sheets shows adhe- sion. The harvested cell sheets can be stratified to reconstruct thicker tissue architectures such as cardiac muscle and liver. We will demonstrate how to utilize these cell sheets for regenerative medicine including ocular surface reconstruction and cardiac tissue repair in clinical settings.

October 31th, 2008, 17h-18h, Room Dw601, Building D , 6th floor.
Dr. Jun-Bo YOON
Department of Electrical Engineering, Korea Advanced Institute of Science and Technology (KAIST)

Image:Pdf_icon.png Retro-Mechanical Era ? From MEMS to NEMS swtiches Image:Info_circle.png

Abstract :
A switch has been playing very important role on our human history. For example, manual phone line switching gave us a great motivation to invent a transistor at Bell lab in around 1950. After dramatic progress in the modern integrated circuit technology, we now are sitting on a position looking back our mechanical switch era. Why? I’d like to discuss the reason with you while presenting recent progresses achieved in MEMS and NEMS switches in this talk

BIO-NANO-ROBO Seminar Series Announcement
September 4th, 2008, 17h-18h', Room Dw601, Building D , 6th floor. Free Entrance
Dr. Janos VOROS
Laboratory of Biosensors and Bioelectronics, Institute for Biomedical Engineering, ETH Zurich, Switzerland
Image:Pdf_icon.png Nanotechnology based approaches to solve biological problems : self-assembling microarray, electrically controlled cell groth, nanoneedle and others Image:Info_circle.png
(link to BIO-NANO-ROBO Seminar Series)

BIO-NANO-ROBO Seminar Series Announcement
July 24th, 2008, 17h-18h, Room Dw601, Building D , 6th floor. Free Entrance
Dr. Teruyuki NAGAMUNE
Dept of Bioengineering, Dept of Chemistry & Biotechnology and Center for NanoBio integration, The University of Tokyo, JAPAN
Image:Pdf_icon.png In Situ Enzymatic Labeling Methods or Membrane Proteins on a Living Cell Image:Info_circle.png
(link to BIO-NANO-ROBO Seminar Series)


July 7, 2008, 17h-18h, Room Dw601, Block D, 6th floor.

Dr. Jean-Pierre AIME
Centre de Physique Moléculaire Optique et Hertzienne (CPMOH), Bordeaux 1 University, France


Image:Pdf_icon.png Carbon Nanotube, Nanoneedle and Nanomeniscus: mechanical and wetting properties of modified AFM tip apex Image:Info_circle.png

Abstract
Dynamic force microscopes (DFM) are very sensitive to variation of minute forces involved in the interaction between the tip and the surface. However, despite numerous efforts, imaging and probing mechanical properties of soft materials in air and water are still chal- lenging experiments at the nm scale. Among various factors determining AFM efficiency, AFM tip remains the central parameter and have been the focus of many creative ideas to improve its stability and resolution. Therefore any new developments able to improve the geometry and size of AFM tips were systematically investigated, in particular use of Carbon Nanotube (CNT), etching process, or Focus Ion Beam to carve a tip. The talk is divided in two parts. The first part is dedicated to the study of the air-liquid interface. We discuss the dynamical properties of a nanomeniscus wetting an oscillating nanoneedle. The second part is dedicated to study of carbon nanotube at the tip apex. As mechanical devices, carbon nanotubes (CNTs) can undergo large nonlinear deformations without permanent damage at the atomic scale.


June 26th, 2008, 17h-18h, Room An301-302, Building A , 3rd floor.

Dr. Arum HAN
Dept. Electrical and Computer Engineering & Dept. - Biomedical, Engineering, Texas A&M University, USA


Image:Pdf_icon.png Microsystem Platform for Cell Culture and Cellular Analysis Image:Info_circle.png

Abstract
Microsystem platforms for co-culture of neuronal cells and for physiological analysis of cells will be presented. A microfluidic compartmentalized co-culture platform has been developed to study axon-glia communications in central nervous system (CNS). This microsystem allows co-culture of neuronal and non-neuronal cells while providing accu- rate control over positions of multiple cell types, localized chemical stimulation, and localized electrical stimulation. The second microfluidic system to be presented is for physiological analysis of cells based on single cell electrical impedance spectroscopy (EIS). The utility of this micro- system in identifying cancer cells and utilizing it for cancer heterogeneity analysis will be discussed.



'April 17th, 2008 - 17h-18h, Room Dw601, Block D, 6th Floor.

Dr. Juergen BRUGGER
Microsystems Laboratory, Ecole Polytechnique Federale de Lausanne(EPFL), Lausanne, Switzerland


Image:Pdf_icon.png Emerging micro/nanopatterning techniques for MEMS/NEMS Image:Info_circle.png

Abstract
Structuring silicon and related materials at micro and nanometer scale is typically done with sophisticated lithography and etching methods. For advanced micro- and nanosys- tems (MEMS/NEMS) more functional materials (complex oxides, nanocrystal polymer blends, and bio-molecules) need to be integrated at multiple length-scales (from nm to mm) and on a variety of substrates (including flexible polymer substrates). This is a grand challenge for surface patterning methods. Recently, alternatives to resist-based lithography have been developed. This talk will first give an overview of emerging nanopatterning methods and will then discuss in more detail two methods that are based on the local deposition of material, i.e. a vacuum-based high-resolution shadow mask process (stencil lithography) and a drop-on-demand dispensing of functional liquids by inkjet printing nanofabrication method.


October 11th, 2007, 17h-18h - Room Dw601, Block D, 6th Floor
Dr. Bong Hyun CHUNG

BioNanotechnology Research in KRIBB - Nano to Diagnosis to Therapy



MEDIA GALLERY

Pictures taken during the lectures and following banquets !!

  • MEDIA GALLERY : Videos of the BIO-NANO-ROBO Seminar Series arrived !!!

CONTACT

For free registration or additional pieces of information, please contact:

->Sebastian VOLZ, Dr. , Dominique FOURMY, Dr. (LIMMS/CNRS-IIS Researchers)

E-mail: Sebastian VOLZ, Dominique FOURMY

ACCESS

Map of the Bio Nano Robo Seminar Series locations on the IIS-Komaba Campus (please check the Seminar Series Schedule page for each month's location) -Link to the "How to Access" and "Maps" website of the IIS Komaba campus: -> IIS

LINKS & SPONSORS

For more informations about the Bio Nano Robo Seminar Series,please visit the useful links to the speakers, sponsors, and friends websites. -> Bio Nano Robo Links

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