Boris BOOM

 boris_boom.jpg Host Laboratory FUJITA LAB.
Position in LIMMS EUJO-LIMMS Researcher (MESA+)
Main Research Topic in LIMMS

NANOTECH - Nanochannel Based STEM Liquid Cell


STEM, nanochannel, liquid imaging


Institute of Industrial Science, The University of Tokyo, 4-6-1 Komaba, Meguro-ku, Tokyo 153-8505, Japan
Phone:+81 (0)3 5452 6036 / Fax:+81 (0)3 5452 6088


MESA+ Institute for Nanotechnology, University of Twente
P.O. Box 217, 7500 AE Enschede, The Netherlands
Phone: + 31 53 489 2715

E-mail b.a.boom at
Download icon_pdf.gifAbstract2015_BBoom.pdf ,


Short resume :
2012-now Actual position
2008 - 2012 Here
2004-2008 Here
2001-2004 Here

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Research Projects in Limms

1- Nanochannel Based STEM Liquid Cell
Context :
Most micromachined devices for use in electron-microscopic imaging in liquid environments consist of 2 separate silicon chips. These chips contain large, thin silicon nitride membranes that are transparent to electrons[1]. This type of device requires critical assembly and sealing steps when preparing  microscopic samples and provides little control on the liquid layer thickness that is used. The new design aims at removing the critical assembly steps for individual devices and gaining more control on the liquid layer thickness in the device. Moreover, this nanochannel based design makes the use of thinner liquid layers feasible, thereby improving the overall achievable imaging resolution.
Objectives & Methods :
The objective of this project is to investigate the achievable resolution of electron-microscopic images in a liquid environment using the new nanochannel liquid cell. The long term goal ultimately is to be able to observe lipid membranes in a liquid environment with an electron microscope and to study the behavior of membrane proteins. Before this can be done, the achievable resolution has to be determined.
Results :
Some tests using gold nanoparticles have been performed to form an idea of the achievable resolution. Smaller particles still have to be tested as well as biological materials, which will show a worse resolution limit. To give an idea of the resolution achieved with this design, some images of gold nanoparticles suspended in a 500nm thick water layer are shown in the attached figures. 


Fig. 1 STEM image of a cluster of 100/50nm gold nanoparticles in a 500nm thick water layer.


Fig. 2 STEM image of a cluster of 50/15nm gold nanoparticles in a 500nm thick water layer.

References and publications :
[1] N. de Jonge and F.M. Ross, Nat. Nanotechnol., 6, p.695, (2011).
Fig. 1 Gold nanoparticle cluster 100/50nm
Fig. 2 Gold nanoparticle cluster 50/15nm

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Main publication List (papers, conferences and patent)







2013 and prior



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