Research

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Scientific Policies

Since its creation, LIMMS has been promoting the concepts of micro and nanotechnology. Based on this expertise, the laboratory operates on three technological fields:

- New developments in nano technologies.

- Micro and nanotechnologies applied to Biology.

- Advanced integration of MEMS and NEMS functions.

 

Since 2016 LIMMS direction has highlighted 4 general fields of applications of these technologies by proposing specific research axis. 

The research axes are related to 

- Integrative Bioengineering, 

- BioMEMS for translational research, 

-Energy, 

-Smart sensors in society. 

 Those 4 fields illustrated our recent MEMS, BioMEMS and Nanotechnologies developments. Although they are not exhaustive, they reflect the orientation of LIMMS in the development of new technologies related to societal demands.  

 In Energy, LIMMS got world-class results on the development of phononic matrix for heat focusing. The LIMMS technologies are in the state of the art on thermionic cooling and thermoelectricity. We are also developing interface research programs on way to power the Internet Of Thing (IOT), leading to propose solution of energy harvester integrated with Smart MEMS devices. 

 In Smart sensors, LIMMS got breakthrough results for sub-atomic surface characterization by AFM, bioreaction sensing, Lab-in-TEM operation like nanoscale thermal transport analysis (in link with the energy axis) and in liquid observation. LIMMS develop new generation of technologies for the IOT, MEMS-VLSI integration. LIMMS cover the “on-chip” integration of distributed control functions and components such as actuators and sensors. Those components can be either silicon based nanopositioners or pL droplet generator. Functions with new materials like cellulose, polymeric flexible substrate and new processes for low cost nanostructuration and large area MEMS have been launched too. LIMMS also leads advanced activity on silicon nanotweezers for molecules and cell handling.

 In Integrative Bioengineering, LIMMS proposes a wide range of organ on chip technology such as the liver model supported by the RHU iLite and the research on neurons chip. LIMMS is able to run droplet-based microfluidic for biochemistry (expanded to a collaboration in France thanks to a 2016-ERC). We also get world-class results in the study of ATPase, in vitro molecular programming and cell-free proteins synthesis in extremely confined fluidic walls.

For BioMEMS Translational research, the characteristic dimensions of the biosystems addressed by our biochips vary from some millimeters for cell/tissue engineering applications, down to few tens of nanometers when we work on the applications to biomolecules. High impact societal actions were obtained in the SMMiLE project. LIMMS activity started with the inauguration in 2014 of a mirror platform of LIMMS in Lille based on the SMMIL-E project, which will focus on research against cancer. In SMMIL-E, the technologies developed in Integrative Bioengineering axis and in Smart Sensors axis (such as the silicon nanotweezers) were successfully transferred to Hospital, Centre Oscar Lambret, for future clinical utilizations. 

Booklets (overall description of Host Labs and Members projects)

2015 

download the booklet edition 2015.

 

 

 

Previous Projects (before 2008)

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