Integrated Nano Electromechanical System for Single Molecule (DNA) Trapping and Characterisation


Project Overview

  • Keywords

  • Context :
  • Objectives :
Theobjective of this project is to demonstrate, for the first time the single molecule manipulation and characterization by micromachined silicon based tweezers. DNA strand being the targeted molecule. Molecule isolation is performed thanks to microfluidics circuits and DNA bundle has been successfully trapped by immersed tweezers.
  • Methods :
The integrated approach for DNA isolation, trapping and manipulation is depicted in fig. 1. DNA molecules are introduced in a microfluidic chip and are moved by DC electrophoresis. A nanochannel separates and isolates the olecules that are finally trapped by a MEMS tweezers in the capturing well. AC signal applied between the opposing tips allows to extent position and trap the molecule between them

Report(s) and Publication(s)

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