BNR #54 by Dr Wojciech Chrzanowski (University of Sydney) Dec. 17th @ PM5:00 - C-lounge
Dr Wojciech Chrzanowski, The University of Sydney
Current Senior Lecturer at the University of Sydney
Appointment Visiting Professor Department of Nanobiomedical Sciences, Dankook University
Qualifications MSc, PhD, DSc
Editorial Duties: Guest Editor Advanced Drug Delivery Reviews; Editorial board member of Journal of Tissue Engineering (2010–); JoVE (2013–) and Engineering of Biomaterials (2010–)
Select awards: Marie Curie Fellowship; Japan Society for the Promotion of Science (JSPS) Invitational Fellowship; Endeavour Executive Award
Career Pubs: excess of 100 peer-reviewed publications, 6 books/chapters, 3 patents
Biointerfaces and bio-nano-characterization – beyond imaging with scanning probe microscopy
The response of the cells to biomaterials is regulated by a few material and surface characteristics. Modifications of these characteristics allow us to modulate cell reasons and guide the cell to migrate, differentiate or inhibit some biological functions. However, to gain a deep understanding of complex pathways that control biological process or materials interactions precise methods and examination tools are required.
Author will present a methodology how to functionalize effectively material surfaces to regulate cells and obtain desired responses in bodily environment. Furthermore, the author will describe the use of scanning probe microscopy techniques to investigate surface interactions with molecules, examine cell nanomechanical properties, and evaluate influence of lipids on cells using combined 3D nanoscale imaging with mechanical probing. In the presentation, the author will highlight current research on theranostics (stimuli responsive drug delivery systems) and particle-particle interaction measurements that were developed to evaluate stability of pharmaceutical products.